| Gene |
Chrm4
|
| Protein Name |
ACM4_RAT |
| Organism |
Rattus norvegicus (Rat) |
| Alternative name(s) |
Muscarinic acetylcholine receptor M4 |
| Protein Family |
G-protein coupled receptor 1 family |
| NCBI Gene ID |
25111
|
| UniProt ID |
P08485
|
| Enzyme Class |
- |
| Molecular Weight |
52921 |
| Protein Length |
478 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
| Function (UniProt annotation) |
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is inhibition of adenylate cyclase. |
| Gene Ontology |
GO:0004930; GO:0004993; GO:0005085; GO:0005737; GO:0005887; GO:0007187; GO:0007197; GO:0007268; GO:0010033; GO:0014069; GO:0016020; GO:0016907; GO:0030054; GO:0030425; GO:0030594; GO:0032279; GO:0040012; GO:0043025; GO:0043679; GO:0098978; GO:0099056; GO:0099061 |
