| Gene |
HIST1H2AG; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM
|
| Protein Name |
H2A1_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Histone H2A type 1 (H2A.1) (Histone H2A/ptl) |
| Protein Family |
Histone H2A family |
| NCBI Gene ID |
8.33E+19
|
| UniProt ID |
P0C0S8
|
| Enzyme Class |
- |
| Molecular Weight |
14091 |
| Protein Length |
130 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Nucleus. Chromosome. |
| Function (UniProt annotation) |
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Gene Ontology |
GO:0000786; GO:0000790; GO:0003677; GO:0005634; GO:0006325; GO:0019899; GO:0046982; GO:0070062 |
