CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	ETS2
Protein Name	ETS2_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Protein C-ets-2
Protein Family	ETS family
NCBI Gene ID	2114
UniProt ID	P15036
Enzyme Class	-
Molecular Weight	53001
Protein Length	469
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus.
Function (UniProt annotation)	Transcription factor activating transcription. Binds specifically the DNA GGAA/T core motif (Ets-binding site or EBS) in gene promoters and stimulates transcription.
Gene Ontology	GO:0000122; GO:0000978; GO:0000981; GO:0001078; GO:0001501; GO:0001712; GO:0003677; GO:0003700; GO:0005634; GO:0005654; GO:0005829; GO:0005886; GO:0006357; GO:0007498; GO:0019904; GO:0030154; GO:0035259; GO:0045893; GO:0045944; GO:0090009

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CAMK2A (Q9UQM7)	Homo sapiens	S246	FPKSRLSSVSVTYCS	0.04	0.1969	-	-	-	-	-	-	In vitro
CAMK2A (Q9UQM7)	Homo sapiens	S310	LDVQRVPSFESFEDD	0.627	0.3249	-	-	-	-	-	-	In vitro and in vivo
CAMK2A (Q9UQM7)	Homo sapiens	S313	QRVPSFESFEDDCSQ	0.957	0.2503	-	-	-	-	-	-	In vitro and in vivo

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa04320	Dorso-ventral axis formation

No NCI Nature pathways found