CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	GAP43
Protein Name	NEUM_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Neuromodulin (Axonal membrane protein GAP-43) (Growth-associated protein 43) (Neural phosphoprotein B-50) (pp46)
Protein Family	Neuromodulin family
NCBI Gene ID	2596
UniProt ID	P17677
Enzyme Class	-
Molecular Weight	24803
Protein Length	238
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cell membrane Note=Cytoplasmic surface of growth cone and synaptic plasma membranes.
Function (UniProt annotation)	This protein is associated with nerve growth. It is a major component of the motile growth cones that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
Gene Ontology	GO:0001786; GO:0005516; GO:0005737; GO:0005886; GO:0007205; GO:0009611; GO:0010001; GO:0014069; GO:0016198; GO:0030054; GO:0031527; GO:0032584; GO:0035727; GO:0040008; GO:0042246; GO:0045165; GO:0051489; GO:0098982; GO:0099150; GO:1901981

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
PHKG1 (Q16816)	Homo sapiens	S77	DEAPVADGVEKKGEG	N/A	N/A	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found