CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	ITPKA
Protein Name	IP3KA_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Inositol-trisphosphate 3-kinase A (EC 2.7.1.127) (Inositol 1,4,5-trisphosphate 3-kinase A) (IP3 3-kinase A) (IP3K A) (InsP 3-kinase A)
Protein Family	Inositol phosphokinase (IPK) family
NCBI Gene ID	3706
UniProt ID	P23677
Enzyme Class	2.7.1.127
Molecular Weight	51009
Protein Length	461
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	ATP + 1D-myo-inositol 1
Localization	N/A
Function (UniProt annotation)	-
Gene Ontology	GO:0004683; GO:0005516; GO:0005524; GO:0005829; GO:0006020; GO:0007165; GO:0008440; GO:0030036; GO:0032958; GO:0043197; GO:0043647; GO:0048167; GO:0048365; GO:0061003; GO:0097062

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CAMK2A (Q9UQM7)	Homo sapiens	T311	EHAQRAVTKPRYMQW	0.826	0.5176	-	-	-	-	9155020	Non high throughput (9155020)	In vitro and in vivo

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa00562	Inositol phosphate metabolism
hsa01100	Metabolic pathways
hsa04020	Calcium signaling pathway
hsa04070	Phosphatidylinositol signaling system

No NCI Nature pathways found