CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	PTPN3
Protein Name	PTN3_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Tyrosine-protein phosphatase non-receptor type 3 (EC 3.1.3.48) (Protein-tyrosine phosphatase H1) (PTP-H1)
Protein Family	Protein-tyrosine phosphatase family
NCBI Gene ID	5774
UniProt ID	P26045
Enzyme Class	3.1.3.48
Molecular Weight	103990
Protein Length	913
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.
Localization	Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.
Function (UniProt annotation)	May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.
Gene Ontology	GO:0001784; GO:0004725; GO:0005737; GO:0005856; GO:0005886; GO:0006470; GO:0008092; GO:0009898; GO:0017080; GO:0042059; GO:0045930; GO:0051045; GO:0051117; GO:0097421; GO:0098902; GO:2000649

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MARK3 (P27448)	Homo sapiens	S359	PAMRRSLSVEHLETK	0.993	0.4149	TP	certain	experimental	62 \| 135 \| 72 \|	9341175	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found