CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	CHAT
Protein Name	CLAT_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Choline O-acetyltransferase (CHOACTase) (ChAT) (Choline acetylase) (EC 2.3.1.6)
Protein Family	Carnitine/choline acetyltransferase family
NCBI Gene ID	1103
UniProt ID	P28329
Enzyme Class	2.3.1.6
Molecular Weight	82536
Protein Length	748
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	Acetyl-CoA + choline = CoA + O-acetylcholine.
Localization	N/A
Function (UniProt annotation)	Catalyzes the reversible synthesis of acetylcholine (ACh) from acetyl CoA and choline at cholinergic synapses.
Gene Ontology	GO:0004102; GO:0005634; GO:0005737; GO:0005829; GO:0006656; GO:0007269; GO:0007274; GO:0008292; GO:0043005; GO:0098793

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CAMK2A (Q9UQM7)	Homo sapiens	T574	VDNIRSATPEALAFV	0.465	0.2034	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa00564	Glycerophospholipid metabolism
hsa04725	Cholinergic synapse

No NCI Nature pathways found