CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	PKLR
Protein Name	KPYR_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Pyruvate kinase PKLR (EC 2.7.1.40) (Pyruvate kinase 1) (Pyruvate kinase isozymes L/R) (R-type/L-type pyruvate kinase) (Red cell/liver pyruvate kinase)
Protein Family	Pyruvate kinase family
NCBI Gene ID	5313
UniProt ID	P30613
Enzyme Class	2.7.1.40
Molecular Weight	61830
Protein Length	574
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	ATP + pyruvate = ADP + phosphoenolpyruvate.
Localization	N/A
Function (UniProt annotation)	Plays a key role in glycolysis.
Gene Ontology	GO:0000287; GO:0001666; GO:0004743; GO:0005524; GO:0005737; GO:0005829; GO:0006096; GO:0009408; GO:0009749; GO:0010226; GO:0016301; GO:0030955; GO:0032869; GO:0033198; GO:0051591; GO:0061621; GO:0070062; GO:0071872

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CAMK1 (Q14012)	Homo sapiens	T48	RASVAQLTQELGTAF	0.038	0.1424	-	-	-	-	-	-	-
CAMK1 (Q14012)	Homo sapiens	T53	QLTQELGTAFFQQQQ	0.045	0.2752	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found