CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	MC4R
Protein Name	MC4R_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Melanocortin receptor 4 (MC4-R)
Protein Family	G-protein coupled receptor 1 family
NCBI Gene ID	4160
UniProt ID	P32245
Enzyme Class	-
Molecular Weight	36943
Protein Length	332
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cell membrane
Function (UniProt annotation)	Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
Gene Ontology	GO:0002024; GO:0004977; GO:0004980; GO:0005634; GO:0005886; GO:0006112; GO:0007186; GO:0007188; GO:0007189; GO:0007631; GO:0016021; GO:0017046; GO:0019222; GO:0030073; GO:0031625; GO:0032868; GO:0042923; GO:0045780; GO:2000252; GO:2000821

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MKNK2 (Q9HBH9)	Homo sapiens	S329	LGGLCDLSSRY____	0.124	0.0044	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S330	GGLCDLSSRY_____	0.093	0.006	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	T312	RSQELRKTFKEIICC	0.809	0.0059	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found