CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	ADD2
Protein Name	ADDB_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Beta-adducin (Erythrocyte adducin subunit beta)
Protein Family	Aldolase class II family
NCBI Gene ID	119
UniProt ID	P35612
Enzyme Class	-
Molecular Weight	80854
Protein Length	726
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Function (UniProt annotation)	Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to the erythrocyte membrane receptor SLC2A1/GLUT1 and may therefore provide a link between the spectrin cytoskeleton to the plasma membrane. Binds to calmodulin. Calmodulin binds preferentially to the beta subunit.
Gene Ontology	GO:0003779; GO:0005198; GO:0005516; GO:0005829; GO:0005856; GO:0007416; GO:0008290; GO:0014069; GO:0019901; GO:0030036; GO:0030097; GO:0030507; GO:0031410; GO:0032092; GO:0042803; GO:0044853; GO:0046982; GO:0050900; GO:0050901; GO:0051015; GO:0051016; GO:0051017; GO:0055085; GO:0065003

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CHEK1 (O14757)	Homo sapiens	S713	KKKFRTPSFLKKSKK	0.935	0.5577	-	-	-	-	-	-	in-vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found