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| Parameter | Value |
|---|---|
| Gene | GJC1 |
| Protein Name | CXG1_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Gap junction gamma-1 protein (Connexin-45) (Cx45) (Gap junction alpha-7 protein) |
| Protein Family | Connexin family |
| NCBI Gene ID | 10052 |
| UniProt ID | P36383 |
| Enzyme Class | - |
| Molecular Weight | 45470 |
| Protein Length | 396 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. |
| Function (UniProt annotation) | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. |
| Gene Ontology | GO:0001570; GO:0005216; GO:0005789; GO:0005886; GO:0005921; GO:0005922; GO:0006936; GO:0007043; GO:0007268; GO:0007601; GO:0014704; GO:0016021; GO:0016264; GO:0048468; GO:0048738; GO:0086014; GO:0086020; GO:0086021; GO:0086053; GO:0086077 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK2A (Q9UQM7) | Homo sapiens | S326 | AQEQQYGSHEENLPA | 0.743 | 0.7036 | - | - | - | - | - | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S381 | SKAGSNKSTASSKSG | 0.68 | 0.8013 | - | - | - | - | - | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S384 | GSNKSTASSKSGDGK | 0.738 | 0.805 | - | - | - | - | - | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S385 | SNKSTASSKSGDGKT | 0.824 | 0.712 | - | - | - | - | - | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S387 | KSTASSKSGDGKTSV | 0.83 | 0.6531 | - | - | - | - | - | - |
|
| CAMK2A (Q9UQM7) | Homo sapiens | S393 | KSGDGKTSVWI____ | 0.988 | 0.5211 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found