| Gene |
HNF4A
|
| Protein Name |
HNF4A_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Hepatocyte nuclear factor 4-alpha (HNF-4-alpha) (Nuclear receptor subfamily 2 group A member 1) (Transcription factor 14) (TCF-14) (Transcription factor HNF-4) |
| Protein Family |
Nuclear hormone receptor family |
| NCBI Gene ID |
3172
|
| UniProt ID |
P41235
|
| Enzyme Class |
- |
| Molecular Weight |
52785 |
| Protein Length |
474 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Nucleus. |
| Function (UniProt annotation) |
Transcriptionally controlled transcription factor. Binds to DNA sites required for the transcription of alpha 1-antitrypsin, apolipoprotein CIII, transthyretin genes and HNF1-alpha. May be essential for development of the liver, kidney and intestine. |
| Gene Ontology |
GO:0000978; GO:0000981; GO:0001077; GO:0001102; GO:0003323; GO:0003677; GO:0003700; GO:0003705; GO:0003707; GO:0004879; GO:0005102; GO:0005504; GO:0005634; GO:0005654; GO:0005737; GO:0006357; GO:0006367; GO:0006591; GO:0006629; GO:0006805; GO:0007548; GO:0007596; GO:0008270; GO:0008285; GO:0009749; GO:0010470; GO:0019216; GO:0023019; GO:0030308; GO:0042593; GO:0042632; GO:0042803; GO:0044212; GO:0045893; GO:0045944; GO:0050796; GO:0055088; GO:0055091; GO:0060395; GO:0060398; GO:0070328; GO:0070365 |
