PID pathway - Regulation of nuclear SMAD2/3 signaling

 
 
Name Protein Names EntryName Phosphorylated by CaM kinases
AKT1 RAC-alpha serine/threonine-protein kinase P31749 MAPKAPK2 | SIK2 | PRKD1 | CAMKK2 |
CDKN1A Cyclin-dependent kinase inhibitor 1 P38936 PIM2 | PIM1 | Stk11 | DAPK3 | NUAK1 | DAPK1 |
CEBPB CCAAT/enhancer-binding protein beta P17676 RPS6KA1 | CAMK2A | CAMK2B | CAMK2D | CAMK2G |
CREB1 Cyclic AMP-responsive element-binding protein 1 P16220 MAPKAPK2 | TSSK4 | CAMK1D | RPS6KA4 | PRKD1 | CAMK4 | RPS6KA5 | RPS6KA3 | RPS6KA2 | RPS6KA1 | CAMK2D | CAMK1 | CAMK1G | CAMK2A | CAMK2B | CAMK2G |
CREBBP CREB-binding protein Q92793 CAMK4 |
EP300 Histone acetyltransferase p300 Q09472 CAMK1 | Camk4 | PRKAA1 | Prkaa2 | CAMK4 | CAMK1D | CAMK1G |
ESR1 Estrogen receptor P03372 RPS6KA3 | RPS6KA1 |
FOS Proto-oncogene c-Fos P01100 RPS6KA2 | RPS6KA1 |
FOXO3 Forkhead box protein O3 O43524 PIM1 | PRKAA2 | PRKAA1 | MAPKAPK5 |
HNF4A Hepatocyte nuclear factor 4-alpha P41235 Prkaa1 | PRKAA1 |
JUN Transcription factor AP-1 P05412 PRKD1 |
MEF2C Myocyte-specific enhancer factor 2C Q06413 RPS6KA2 | MYLK2 |
RUNX3 Runt-related transcription factor 3 Q13761 PIM1 |
SMAD2 Mothers against decapentaplegic homolog 2 Q15796 Melk | CAMK2A | MELK |
SMAD4 Mothers against decapentaplegic homolog 4 Q13485 Melk | STK11 | MELK |