CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	CCR5
Protein Name	CCR5_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	C-C chemokine receptor type 5 (C-C CKR-5) (CC-CKR-5) (CCR-5) (CCR5) (CHEMR13) (HIV-1 fusion coreceptor) (CD antigen CD195)
Protein Family	G-protein coupled receptor 1 family
NCBI Gene ID	1234
UniProt ID	P51681
Enzyme Class	-
Molecular Weight	40524
Protein Length	352
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cell membrane
Function (UniProt annotation)	Receptor for a number of inflammatory CC-chemokines including CCL3/MIP-1-alpha, CCL4/MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation.
Gene Ontology	GO:0000165; GO:0001618; GO:0002407; GO:0003779; GO:0004435; GO:0004950; GO:0005737; GO:0005768; GO:0005886; GO:0005887; GO:0006816; GO:0006935; GO:0006954; GO:0006955; GO:0006968; GO:0007166; GO:0007186; GO:0007204; GO:0007267; GO:0009897; GO:0009986; GO:0014808; GO:0015026; GO:0016493; GO:0019064; GO:0019221; GO:0019722; GO:0019956; GO:0019957; GO:0023052; GO:0030260; GO:0060326; GO:0070723; GO:0071222; GO:0071791; GO:2000110

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MKNK2 (Q9HBH9)	Homo sapiens	S336	QEAPERASSVYTRST	0.802	0.2817	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S337	EAPERASSVYTRSTG	0.974	0.3872	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S349	STGEQEISVGL____	0.726	0.2094	-	-	-	-	-	-	-
MKNK2 (Q9HBH9)	Homo sapiens	S342	ASSVYTRSTGEQEIS	0.835	0.2752	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found