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| Parameter | Value |
|---|---|
| Gene | HNRNPM |
| Protein Name | HNRPM_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Heterogeneous nuclear ribonucleoprotein M (hnRNP M) |
| Protein Family | N/A |
| NCBI Gene ID | 4670 |
| UniProt ID | P52272 |
| Enzyme Class | - |
| Molecular Weight | 77516 |
| Protein Length | 730 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Nucleus, nucleolus |
| Function (UniProt annotation) | Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. |
| Gene Ontology | GO:0000380; GO:0000398; GO:0003723; GO:0003729; GO:0005634; GO:0005654; GO:0005681; GO:0005730; GO:0005737; GO:0008543; GO:0016020; GO:0016070; GO:0016363; GO:0019904; GO:0042382; GO:0062023; GO:0070062; GO:0071013; GO:0071014; GO:1990904; GO:2000815 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHEK1 (O14757) | Homo sapiens | S432 | HGMDRVGSEIERMGL | 0.975 | 0.4292 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found