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Parameter | Value |
---|---|
Gene | NRXN1 |
Protein Name | NRX1B_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | Neurexin-1-beta (Neurexin I-beta) |
Protein Family | Neurexin family |
NCBI Gene ID | 9378 |
UniProt ID | P58400 |
Enzyme Class | - |
Molecular Weight | 50424 |
Protein Length | 472 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Note=Localized on the pre-synaptic membrane. |
Function (UniProt annotation) | Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity). |
Gene Ontology | GO:0001525; GO:0004888; GO:0005102; GO:0005105; GO:0005783; GO:0005886; GO:0007157; GO:0007158; GO:0007165; GO:0007416; GO:0007612; GO:0009986; GO:0010628; GO:0010629; GO:0010739; GO:0016339; GO:0021707; GO:0023041; GO:0030054; GO:0030139; GO:0030534; GO:0031175; GO:0031965; GO:0031982; GO:0033138; GO:0035176; GO:0035418; GO:0042734; GO:0043025; GO:0044295; GO:0045184; GO:0045743; GO:0046872; GO:0048306; GO:0050839; GO:0051490; GO:0051897; GO:0051965; GO:0051968; GO:0070374; GO:0071277; GO:0071625; GO:0090126; GO:0097091; GO:0097104; GO:0097105; GO:0097109; GO:0097112; GO:0097114; GO:0097116; GO:0097117; GO:0097118; GO:0097119; GO:0097120; GO:0098793; GO:0099056; GO:1900020; GO:1903078; GO:1905520; GO:2000310; GO:2000311; GO:2000463 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
CASK (O14936) | Homo sapiens | S424 | MYKYRNRDEGSYHVD | N/A | N/A | - | - | - | - | - | - |
|
CASK (O14936) | Homo sapiens | S428 | KQPSSAKSSNKNKKN | N/A | N/A | - | - | - | - | - | - |
|
CASK (O14936) | Homo sapiens | S425 | VKEKQPSSAKSSNKN | N/A | N/A | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found