Parameter | Value |
---|---|
Gene | Evl |
Protein Name | EVL_MOUSE |
Organism | Mus musculus (Mouse) |
Alternative name(s) | Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like) |
Protein Family | Ena/VASP family |
NCBI Gene ID | 14026 |
UniProt ID | P70429 |
Enzyme Class | - |
Molecular Weight | 44337 |
Protein Length | 414 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Cytoplasm, cytoskeleton |
Function (UniProt annotation) | Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. |
Gene Ontology | GO:0003779; GO:0005522; GO:0005737; GO:0005856; GO:0005925; GO:0007411; GO:0008154; GO:0010633; GO:0017124; GO:0030027; GO:0030048; GO:0030168; GO:0030838; GO:0045010; GO:0045335; GO:0051016; GO:0051289; GO:0051496; GO:0071346; GO:1900028 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
PRKD1 (Q15139) | Homo sapiens | S343 | SLLSRTPSVAKSPEA | N/A | 0.8493 | TP | certain | experimental | 72 | 73 | 9 | 55 | 40 | 23 | | 19000756 | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found