| Parameter | Value |
|---|---|
| Gene | Evl |
| Protein Name | EVL_MOUSE |
| Organism | Mus musculus (Mouse) |
| Alternative name(s) | Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like) |
| Protein Family | Ena/VASP family |
| NCBI Gene ID | 14026 |
| UniProt ID | P70429 |
| Enzyme Class | - |
| Molecular Weight | 44337 |
| Protein Length | 414 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Cytoplasm, cytoskeleton |
| Function (UniProt annotation) | Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. |
| Gene Ontology | GO:0003779; GO:0005522; GO:0005737; GO:0005856; GO:0005925; GO:0007411; GO:0008154; GO:0010633; GO:0017124; GO:0030027; GO:0030048; GO:0030168; GO:0030838; GO:0045010; GO:0045335; GO:0051016; GO:0051289; GO:0051496; GO:0071346; GO:1900028 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRKD1 (Q15139) | Homo sapiens | S343 | SLLSRTPSVAKSPEA | N/A | 0.8493 | TP | certain | experimental | 72 | 73 | 9 | 55 | 40 | 23 | | 19000756 | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found