Graphics credits: COMPARTMENTS | More Info
| Parameter | Value |
|---|---|
| Gene | SLC6A3 |
| Protein Name | SC6A3_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Sodium-dependent dopamine transporter (DA transporter) (DAT) (Solute carrier family 6 member 3) |
| Protein Family | Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family |
| NCBI Gene ID | 6531 |
| UniProt ID | Q01959 |
| Enzyme Class | - |
| Molecular Weight | 68495 |
| Protein Length | 620 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Cell membrane |
| Function (UniProt annotation) | Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals. |
| Gene Ontology | GO:0001504; GO:0002020; GO:0005102; GO:0005328; GO:0005330; GO:0005737; GO:0005886; GO:0007568; GO:0007595; GO:0007608; GO:0007626; GO:0008504; GO:0009986; GO:0010039; GO:0015844; GO:0015872; GO:0016021; GO:0016600; GO:0021984; GO:0030424; GO:0035094; GO:0035240; GO:0040018; GO:0042053; GO:0042136; GO:0042220; GO:0042416; GO:0042420; GO:0043005; GO:0043025; GO:0044877; GO:0045121; GO:0045471; GO:0046872; GO:0047485; GO:0051591; GO:0051721; GO:0060134; GO:0090494; GO:0098691; GO:0099055; GO:0099056 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMK2A (Q9UQM7) | Homo sapiens | S13 | CSVGLMSSVVAPAKE | 0.5 | 0.268 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found