Graphics credits: COMPARTMENTS | More Info
| Parameter | Value |
|---|---|
| Gene | FOXM1 |
| Protein Name | FOXM1_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Forkhead box protein M1 (Forkhead-related protein FKHL16) (Hepatocyte nuclear factor 3 forkhead homolog 11) (HFH-11) (HNF-3/fork-head homolog 11) (M-phase phosphoprotein 2) (MPM-2 reactive phosphoprotein 2) (Transcription factor Trident) (Winged-helix factor from INS-1 cells) |
| Protein Family | N/A |
| NCBI Gene ID | 2305 |
| UniProt ID | Q08050 |
| Enzyme Class | - |
| Molecular Weight | 84283 |
| Protein Length | 763 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Nucleus. |
| Function (UniProt annotation) | Transcriptional factor regulating the expression of cell cycle genes essential for DNA replication and mitosis. Plays a role in the control of cell proliferation. Plays also a role in DNA breaks repair participating in the DNA damage checkpoint response. |
| Gene Ontology | GO:0000086; GO:0000122; GO:0000977; GO:0000981; GO:0001227; GO:0001558; GO:0003677; GO:0003700; GO:0005654; GO:0006281; GO:0006366; GO:0006978; GO:0008284; GO:0019901; GO:0032873; GO:0042127; GO:0045892; GO:0045893; GO:0045944; GO:0046578; GO:0051726; GO:0071156; GO:0090344; GO:2000377; GO:2000781 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHEK2 (O96017) | Homo sapiens | S361 | PLLPRVSSYLVPIQF | N/A | N/A | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found