CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	GTF3C1
Protein Name	TF3C1_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha)
Protein Family	TFIIIC subunit 1 family
NCBI Gene ID	2975
UniProt ID	Q12789
Enzyme Class	-
Molecular Weight	238875
Protein Length	2109
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus.
Function (UniProt annotation)	Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element.
Gene Ontology	GO:0000127; GO:0001002; GO:0001003; GO:0005634; GO:0005654; GO:0005730; GO:0006383; GO:0006384; GO:0009303; GO:0009304; GO:0016020; GO:0042791; GO:0042797; GO:1990904

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CHEK1 (O14757)	Homo sapiens	S667	VRLVRNLSEEGLLRL	0.671	0.2849	-	-	-	-	-	-	in-vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found