CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	RABEP1
Protein Name	RABE1_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Rab GTPase-binding effector protein 1 (Rabaptin-4) (Rabaptin-5) (Rabaptin-5alpha) (Renal carcinoma antigen NY-REN-17)
Protein Family	Rabaptin family
NCBI Gene ID	9135
UniProt ID	Q15276
Enzyme Class	-
Molecular Weight	99290
Protein Length	862
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cytoplasm. Early endosome. Recycling endosome. Cytoplasmic vesicle.
Function (UniProt annotation)	Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712). Stimulates RABGEF1 mediated nucleotide exchange on RAB5A.
Gene Ontology	GO:0005096; GO:0005768; GO:0005769; GO:0006897; GO:0006915; GO:0008083; GO:0015031; GO:0016192; GO:0019904; GO:0030139; GO:0031901; GO:0032991; GO:0042803; GO:0043231; GO:0055037; GO:0061025

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
PRKD1 (Q15139)	Homo sapiens	S407	DGLRRAQSTDSLGTS	0.942	0.5419	-	-	-	-	-	-	in-vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found