CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	OCLN
Protein Name	OCLN_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Occludin
Protein Family	ELL/occludin family
NCBI Gene ID	100506658
UniProt ID	Q16625
Enzyme Class	-
Molecular Weight	59144
Protein Length	522
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cell membrane
Function (UniProt annotation)	May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions.
Gene Ontology	GO:0005886; GO:0005911; GO:0005923; GO:0016021; GO:0016324; GO:0016327; GO:0016328; GO:0019904; GO:0030054; GO:0030139; GO:0031410; GO:0045216; GO:0065003; GO:0070673; GO:0070830; GO:0071356; GO:2000810

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CAMK2D (Q13557)	Homo sapiens	S471	LDDYREESEEYMAAA	0.691	0.5854	-	-	-	-	-	-	in-vitro
CAMK2B (Q13554)	Homo sapiens	S471	LDDYREESEEYMAAA	0.691	0.5854	-	-	-	-	-	-	in-vitro
CAMK2G (Q13555)	Homo sapiens	S471	LDDYREESEEYMAAA	0.691	0.5854	-	-	-	-	-	-	in-vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found