STRING | IntAct | MINT

Open Targets | OMIM

ATP + a protein = ADP + a phosphoprotein.

Sarcoplasmic reticulum membrane Peripheral membrane protein Cytoplasmic side

Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning.

GO:0000165; GO:0004674; GO:0004683; GO:0004723; GO:0005088; GO:0005516; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0007399; GO:0014733; GO:0016020; GO:0030073; GO:0030154; GO:0030666; GO:0033017; GO:0042802; GO:0042803; GO:0043005; GO:0051259; GO:0051924; GO:0060333