Graphics credits: COMPARTMENTS | More Info
| Parameter | Value |
|---|---|
| Gene | INF2 |
| Protein Name | INF2_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Inverted formin-2 (HBEBP2-binding protein C) |
| Protein Family | Formin homology family |
| NCBI Gene ID | 64423 |
| UniProt ID | Q27J81 |
| Enzyme Class | - |
| Molecular Weight | 135624 |
| Protein Length | 1249 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Cytoplasm, perinuclear region |
| Function (UniProt annotation) | Severs actin filaments and accelerates their polymerization and depolymerization. |
| Gene Ontology | GO:0003779; GO:0017048; GO:0030036; GO:0048471; GO:0090140 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHEK1 (O14757) | Homo sapiens | S574 | LNWQKLPSNVAREHN | 0.608 | 0.4541 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found