Gene |
N/A
|
Protein Name |
Q5U0A5_HUMAN |
Organism |
Homo sapiens (Human) |
Alternative name(s) |
DNA repair protein RAD51 homolog |
Protein Family |
RecA family |
NCBI Gene ID |
N/A
|
UniProt ID |
Q5U0A5
|
Enzyme Class |
- |
Molecular Weight |
37038 |
Protein Length |
339 |
Protein Domain |
InterPro |
Pfam
|
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
Gene Expression |
Gene Expression Atlas
|
Function and Disease |
OMIM |
Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
Catalytic Activity (UniProt annotation) |
- |
Localization |
Nucleus |
Function (UniProt annotation) |
Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. |
Gene Ontology |
GO:0000150; GO:0000724; GO:0003690; GO:0003697; GO:0005524; GO:0005634; GO:0008094; GO:1990426 |