| Gene |
Dlg1
|
| Protein Name |
DLG1_RAT |
| Organism |
Rattus norvegicus (Rat) |
| Alternative name(s) |
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) |
| Protein Family |
MAGUK family |
| NCBI Gene ID |
25252
|
| UniProt ID |
Q62696
|
| Enzyme Class |
- |
| Molecular Weight |
100571 |
| Protein Length |
911 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Membrane |
| Function (UniProt annotation) |
Essential multidomain scaffolding protein required for normal development (By similarity). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel (By similarity). May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. |
| Gene Ontology |
GO:0001935; GO:0005789; GO:0005829; GO:0005886; GO:0005902; GO:0007015; GO:0007155; GO:0007268; GO:0008022; GO:0009925; GO:0014069; GO:0016323; GO:0016324; GO:0019894; GO:0019901; GO:0019902; GO:0030054; GO:0030165; GO:0030315; GO:0030425; GO:0030866; GO:0031594; GO:0032880; GO:0033270; GO:0035255; GO:0042734; GO:0043005; GO:0043113; GO:0043268; GO:0045197; GO:0045211; GO:0045930; GO:0097120; GO:0098609; GO:0098839; GO:0098978; GO:0099092; GO:0099645 |
