| Gene |
Myh9
|
| Protein Name |
MYH9_RAT |
| Organism |
Rattus norvegicus (Rat) |
| Alternative name(s) |
Myosin-9 (Cellular myosin heavy chain, type A) (Myosin heavy chain 9) (Myosin heavy chain, non-muscle IIa) (Non-muscle myosin heavy chain A) (NMMHC-A) (Non-muscle myosin heavy chain IIa) (NMMHC II-a) (NMMHC-IIA) |
| Protein Family |
TRAFAC class myosin-kinesin ATPase superfamily |
| NCBI Gene ID |
N/A
|
| UniProt ID |
Q62812
|
| Enzyme Class |
- |
| Molecular Weight |
226338 |
| Protein Length |
1961 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm, cytoskeleton |
| Function (UniProt annotation) |
During cell spreading, plays an important role in cytoskeleton reorganization, focal contacts formation (in the margins but not the central part of spreading cells), and lamellipodial retraction; this function is mechanically antagonized by MYH10 (By similarity). Cellular myosin that appears to play a role in cytokinesis, cell shape, and specialized functions such as secretion and capping. |
| Gene Ontology |
GO:0000146; GO:0001525; GO:0001725; GO:0001726; GO:0001965; GO:0005178; GO:0005391; GO:0005516; GO:0005524; GO:0005634; GO:0005737; GO:0005739; GO:0005826; GO:0005829; GO:0005884; GO:0005886; GO:0005903; GO:0006509; GO:0008360; GO:0015031; GO:0015629; GO:0016324; GO:0016328; GO:0016459; GO:0016887; GO:0019901; GO:0030027; GO:0030048; GO:0030220; GO:0030224; GO:0031252; GO:0031532; GO:0031762; GO:0032154; GO:0032506; GO:0032962; GO:0032991; GO:0035774; GO:0036120; GO:0042699; GO:0042802; GO:0042803; GO:0043495; GO:0043534; GO:0045745; GO:0045807; GO:0050766; GO:0051015; GO:0051017; GO:0051482; GO:0051894; GO:0070374; GO:0070650; GO:0071260; GO:0097110; GO:0098609; GO:1904753 |
