Parameter | Value |
---|---|
Gene | Sln |
Protein Name | SARCO_RAT |
Organism | Rattus norvegicus (Rat) |
Alternative name(s) | Sarcolipin |
Protein Family | Sarcolipin family |
NCBI Gene ID | 367086 |
UniProt ID | Q6SLE7 |
Enzyme Class | - |
Molecular Weight | 3808 |
Protein Length | 31 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Sarcoplasmic reticulum membrane |
Function (UniProt annotation) | Reversibly inhibits the activity of ATP2A1 in sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in muscle. Required for muscle-based, non-shivering thermogenesis (By similarity). |
Gene Ontology | GO:0016021; GO:0016529; GO:0030234; GO:0033017; GO:0051924; GO:0070296; GO:0120162; GO:1901077; GO:1901894 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
CAMK2A (Q9UQM7) | Homo sapiens | T5 | ___MERSTQELFINF | N/A | 0.0085 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found