CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	TBC1D1
Protein Name	TBCD1_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	TBC1 domain family member 1
Protein Family	N/A
NCBI Gene ID	23216
UniProt ID	Q86TI0
Enzyme Class	-
Molecular Weight	133084
Protein Length	1168
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus
Function (UniProt annotation)	May act as a GTPase-activating protein for Rab family protein(s). May play a role in the cell cycle and differentiation of various tissues. Involved in the trafficking and translocation of GLUT4-containing vesicles and insulin-stimulated glucose uptake into cells (By similarity).
Gene Ontology	GO:0005096; GO:0005634; GO:0005829; GO:0006886; GO:0017137; GO:0032880; GO:0061024; GO:0090630

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
PRKAA1 (Q13131)	Homo sapiens	S237	RPMRKSFSQPGLRSL	0.733	0.4292	TP	certain	experimental	55 \| 8 \| 73 \| 214 \|	17995453	-	In vitro and in vivo
PRKAA1 (Q13131)	Homo sapiens	T596	AFRRRANTLSHFPIE	0.867	0.5493	TP	certain	experimental	55 \| 73 \| 214 \|	17995453	-	In vitro
PRKAA2 (P54646)	Homo sapiens	S237	RPMRKSFSQPGLRSL	0.733	0.4292	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found