CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	KSR1
Protein Name	KSR1_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Kinase suppressor of Ras 1
Protein Family	Protein kinase superfamily
NCBI Gene ID	8844
UniProt ID	Q8IVT5
Enzyme Class	-
Molecular Weight	102160
Protein Length	923
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cytoplasm
Function (UniProt annotation)	Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity by itself.
Gene Ontology	GO:0000165; GO:0004672; GO:0005078; GO:0005524; GO:0005783; GO:0005789; GO:0005829; GO:0007265; GO:0008022; GO:0016020; GO:0019933; GO:0031434; GO:0032587; GO:0032991; GO:0042127; GO:0043405; GO:0043410; GO:0046872; GO:0051087; GO:0051879; GO:0071889

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MARK3 (P27448)	Homo sapiens	S406	TRLRRTESVPSDINN	0.7	0.6183	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa05152	Tuberculosis

NCI Nature PID Pathways

Pathway ID	Pathway Name
ceramidepathway	Ceramide signaling pathway