CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	PPP1R12A
Protein Name	MYPT1_CHICK
Organism	Gallus gallus (Chicken)
Alternative name(s)	Protein phosphatase 1 regulatory subunit 12A (130 kDa myosin-binding subunit of smooth muscle myosin phosphatase) (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (PP1M subunit M110) (Protein phosphatase myosin-binding subunit)
Protein Family	N/A
NCBI Gene ID	396020
UniProt ID	Q90623
Enzyme Class	-
Molecular Weight	111606
Protein Length	1004
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cytoplasm
Function (UniProt annotation)	Regulates myosin phosphatase activity.
Gene Ontology	GO:0000278; GO:0000776; GO:0004857; GO:0005737; GO:0005813; GO:0005829; GO:0006470; GO:0007098; GO:0007165; GO:0015629; GO:0019208; GO:0019901; GO:0030018; GO:0030155; GO:0031672; GO:0035507; GO:0035508; GO:0035690; GO:0045944; GO:0046822; GO:0071889; GO:0072357

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
DAPK3 (O43293)	Homo sapiens	S849	RPREKRRSTGVSFWT	N/A	0.6712	-	-	-	-	-	-	In vitro
DAPK3 (O43293)	Homo sapiens	T695	ARQSRRSTQGVTLTD	N/A	0.8085	-	-	-	-	11226254, 12030846	Non high throughput (11226254, 12030846)	In vitro and in vivo
DAPK3 (O43293)	Homo sapiens	T716	TIGRSRSTRTREQEN	N/A	0.8565	-	-	-	-	-	-	In vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
gga04270	Vascular smooth muscle contraction
gga04270	Vascular smooth muscle contraction
gga04510	Focal adhesion
gga04510	Focal adhesion
gga04810	Regulation of actin cytoskeleton
gga04810	Regulation of actin cytoskeleton

No NCI Nature pathways found