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| Parameter | Value |
|---|---|
| Gene | FYTTD1 |
| Protein Name | UIF_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | UAP56-interacting factor (Forty-two-three domain-containing protein 1) (Protein 40-2-3) |
| Protein Family | UIF family |
| NCBI Gene ID | 84248 |
| UniProt ID | Q96QD9 |
| Enzyme Class | - |
| Molecular Weight | 35818 |
| Protein Length | 318 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Nucleus, nucleoplasm |
| Function (UniProt annotation) | Required for mRNA export from the nucleus to the cytoplasm. Acts as an adapter that uses the DDX39B/UAP56-NFX1 pathway to ensure efficient mRNA export and delivering to the nuclear pore. Associates with spliced and unspliced mRNAs simultaneously with ALYREF/THOC4. |
| Gene Ontology | GO:0003723; GO:0003729; GO:0005654; GO:0006406; GO:0016607 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHEK1 (O14757) | Homo sapiens | T205 | KVQAQLNTEQLLDDV | 0.072 | 0.3948 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found