CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	FEZ1
Protein Name	FEZ1_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Fasciculation and elongation protein zeta-1 (Zygin I) (Zygin-1)
Protein Family	Zygin family
NCBI Gene ID	9638
UniProt ID	Q99689
Enzyme Class	-
Molecular Weight	45119
Protein Length	392
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome
Function (UniProt annotation)	May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules.
Gene Ontology	GO:0005737; GO:0005794; GO:0005815; GO:0005874; GO:0005886; GO:0007155; GO:0007399; GO:0007411; GO:0030424; GO:1902902

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MARK1 (Q9P0L2)	Homo sapiens	S58	SEIISFKSMEDLVNE	0.828	0.4051	-	-	-	-	-	-	in-vitro and in-vivo
MARK2 (Q7KZI7)	Homo sapiens	S58	SEIISFKSMEDLVNE	0.828	0.4051	-	-	-	-	-	-	in-vitro and in-vivo
MARK3 (P27448)	Homo sapiens	S58	SEIISFKSMEDLVNE	0.828	0.4051	-	-	-	-	-	-	in-vitro and in-vivo

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found