Graphics credits: COMPARTMENTS | More Info
Parameter | Value |
---|---|
Gene | PKP2 |
Protein Name | PKP2_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | Plakophilin-2 |
Protein Family | Beta-catenin family |
NCBI Gene ID | 5318 |
UniProt ID | Q99959 |
Enzyme Class | - |
Molecular Weight | 97415 |
Protein Length | 881 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Nucleus Note=Nuclear and associated with desmosomes. |
Function (UniProt annotation) | May play a role in junctional plaques. |
Gene Ontology | GO:0001533; GO:0002159; GO:0005080; GO:0005634; GO:0005654; GO:0005737; GO:0005882; GO:0005886; GO:0005911; GO:0005912; GO:0005913; GO:0007043; GO:0007507; GO:0010765; GO:0014704; GO:0016021; GO:0017080; GO:0019215; GO:0030054; GO:0030057; GO:0031424; GO:0032947; GO:0034334; GO:0044325; GO:0045110; GO:0045294; GO:0045296; GO:0048496; GO:0055010; GO:0070268; GO:0072659; GO:0086002; GO:0086005; GO:0086019; GO:0086064; GO:0086073; GO:0086083; GO:0086091; GO:0098609; GO:0098911 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
MARK3 (P27448) | Homo sapiens | S82 | GNLHRTSSVPEYVYN | 0.872 | 0.4369 | TP | certain | experimental | 72 | 137 | 135 | 9 | | 12941695 | - |
|
Reactome Pathways
KEGG Pathways
Pathway ID | Pathway Name |
---|---|
hsa05412 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) |
No NCI Nature pathways found