| Gene |
MYBBP1A
|
| Protein Name |
MBB1A_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Myb-binding protein 1A |
| Protein Family |
MYBBP1A family |
| NCBI Gene ID |
10514
|
| UniProt ID |
Q9BQG0
|
| Enzyme Class |
- |
| Molecular Weight |
148855 |
| Protein Length |
1328 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm |
| Function (UniProt annotation) |
May activate or repress transcription via interactions with sequence specific DNA-binding proteins (By similarity). Repression may be mediated at least in part by histone deacetylase activity (HDAC activity) (By similarity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2 (By similarity). Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter (By similarity). Has a role in rRNA biogenesis together with PWP1 (PubMed:29065309). |
| Gene Ontology |
GO:0001649; GO:0003714; GO:0003723; GO:0005634; GO:0005654; GO:0005730; GO:0005737; GO:0006355; GO:0008134; GO:0016020; GO:0022904; GO:0032922; GO:0042149; GO:0042254; GO:0042564; GO:0043231; GO:0043565; GO:0045815; GO:0045892; GO:0070888; GO:0071158; GO:0072332; GO:2000210 |
