| Gene |
CEP250
|
| Protein Name |
CP250_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Centrosome-associated protein CEP250 (250 kDa centrosomal protein) (Cep250) (Centrosomal Nek2-associated protein 1) (C-Nap1) (Centrosomal protein 2) |
| Protein Family |
N/A |
| NCBI Gene ID |
11190
|
| UniProt ID |
Q9BV73
|
| Enzyme Class |
- |
| Molecular Weight |
281137 |
| Protein Length |
2442 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm, perinuclear region Note=Component of the core centrosome. In interphase cells, it specifically associates with the proximal ends of both mother and daughter centrioles. Associates with the centrosome in interphase cells. In mitotic cells, it dissociates from the mitotic spindle poles. At the end of cell division, it reaccumulates at centrosomes. In photoreceptors, found at the proximal ends of basal bodies. |
| Function (UniProt annotation) |
Probably plays an important role in centrosome cohesion during interphase. |
| Gene Ontology |
GO:0000086; GO:0000278; GO:0005813; GO:0005814; GO:0005815; GO:0005829; GO:0005929; GO:0008022; GO:0008104; GO:0010389; GO:0010457; GO:0019901; GO:0019904; GO:0030997; GO:0032991; GO:0033365; GO:0048471; GO:0070062; GO:0097711; GO:1904781; GO:1905515 |
