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| Parameter | Value |
|---|---|
| Gene | KIFC1 |
| Protein Name | KIFC1_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Kinesin-like protein KIFC1 (Kinesin-like protein 2) (Kinesin-related protein HSET) |
| Protein Family | TRAFAC class myosin-kinesin ATPase superfamily |
| NCBI Gene ID | 3833 |
| UniProt ID | Q9BW19 |
| Enzyme Class | - |
| Molecular Weight | 73748 |
| Protein Length | 673 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Nucleus |
| Function (UniProt annotation) | Minus end-directed microtubule-dependent motor required for bipolar spindle formation (PubMed:15843429). May contribute to movement of early endocytic vesicles (By similarity). Regulates cilium formation and structure (By similarity). |
| Gene Ontology | GO:0000070; GO:0003777; GO:0005524; GO:0005634; GO:0005769; GO:0005815; GO:0005871; GO:0005874; GO:0007018; GO:0007080; GO:0007283; GO:0008017; GO:0016020; GO:0016887; GO:0051301; GO:0072686; GO:0090307 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHEK1 (O14757) | Homo sapiens | S26 | RPLIKAPSQLPLSGS | 0.194 | 0.7163 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found