CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	OSBPL11
Protein Name	OSB11_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Oxysterol-binding protein-related protein 11 (ORP-11) (OSBP-related protein 11)
Protein Family	OSBP family
NCBI Gene ID	114885
UniProt ID	Q9BXB4
Enzyme Class	-
Molecular Weight	83643
Protein Length	747
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Late endosome membrane Note=Localizes at the Golgi-late endosome interface.
Function (UniProt annotation)	Plays a role in regulating ADIPOQ and FABP4 levels in differentiating adipocytes and is also involved in regulation of adipocyte triglyceride storage (PubMed:23028956). Weakly binds 25-hydroxycholesterol (PubMed:17428193).
Gene Ontology	GO:0005654; GO:0005794; GO:0005829; GO:0008289; GO:0010890; GO:0015248; GO:0016020; GO:0031902; GO:0032934; GO:0043231; GO:0045444

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CHEK1 (O14757)	Homo sapiens	S189	PISQRRPSQNAISFF	0.918	0.5211	-	-	-	-	-	-	in-vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found