CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	FANCE
Protein Name	FANCE_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Fanconi anemia group E protein (Protein FACE)
Protein Family	N/A
NCBI Gene ID	2178
UniProt ID	Q9HB96
Enzyme Class	-
Molecular Weight	58711
Protein Length	536
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus
Function (UniProt annotation)	As part of the Fanconi anemia (FA) complex functions in DNA cross-links repair. Required for the nuclear accumulation of FANCC and provides a critical bridge between the FA complex and FANCD2.
Gene Ontology	GO:0005634; GO:0005654; GO:0036297; GO:0043240

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CHEK1 (O14757)	Homo sapiens	T346	LGLLRLCTWLLALSP	0.171	0.0281	TP	certain	experimental	72 \| 9 \| 73 \| 55 \|	17296736	-	-
CHEK1 (O14757)	Homo sapiens	S374	LFLGRILSLTSSASR	0.764	0.0568	-	-	-	-	-	-	In vitro and in vivo

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

NCI Nature PID Pathways

Pathway ID	Pathway Name
bard1pathway	BARD1 signaling events