| Gene |
Rims1
|
| Protein Name |
RIMS1_RAT |
| Organism |
Rattus norvegicus (Rat) |
| Alternative name(s) |
Regulating synaptic membrane exocytosis protein 1 (Rab-3-interacting molecule 1) (RIM 1) |
| Protein Family |
N/A |
| NCBI Gene ID |
84556
|
| UniProt ID |
Q9JIR4
|
| Enzyme Class |
- |
| Molecular Weight |
179655 |
| Protein Length |
1615 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cell membrane; Peripheral membrane protein. Cell junction, synapse. Cell junction, synapse, presynaptic cell membrane Note=Associated with plasma membranes from synaptic junctions. Not detected in synaptic vesicles. Detected in presynaptic nerve terminals close to the active zone. Detected in synaptic ribbons of ribbon synapses of retinal photoreceptor cells. |
| Function (UniProt annotation) |
Rab effector involved in exocytosis. May act as scaffold protein that regulates neurotransmitter release at the active zone. Essential for maintaining normal probability of neurotransmitter release and for regulating release during short-term synaptic plasticity. Plays a role in dendrite formation by melanocytes. |
| Gene Ontology |
GO:0005886; GO:0006886; GO:0010628; GO:0010808; GO:0017124; GO:0017137; GO:0019901; GO:0030054; GO:0030154; GO:0031632; GO:0042391; GO:0042734; GO:0044325; GO:0045202; GO:0046872; GO:0048167; GO:0048788; GO:0048791; GO:0050806; GO:0060291; GO:0097151; GO:0098831; GO:0098978; GO:2000300; GO:2000463 |
