| Gene |
GCM1
|
| Protein Name |
GCM1_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Chorion-specific transcription factor GCMa (hGCMa) (GCM motif protein 1) (Glial cells missing homolog 1) |
| Protein Family |
N/A |
| NCBI Gene ID |
8521
|
| UniProt ID |
Q9NP62
|
| Enzyme Class |
- |
| Molecular Weight |
49268 |
| Protein Length |
436 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Nucleus |
| Function (UniProt annotation) |
Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes (PubMed:10542267, PubMed:18160678). Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer (PubMed:10542267). Binds to the SYDE1 promoter (PubMed:27917469). Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (PubMed:19219068). |
| Gene Ontology |
GO:0000978; GO:0000981; GO:0001077; GO:0003677; GO:0003700; GO:0005634; GO:0005667; GO:0006355; GO:0006366; GO:0008134; GO:0008270; GO:0009653; GO:0042826; GO:0045944; GO:0060018; GO:0060143; GO:0060670; GO:0060706; GO:0060800 |
