Graphics credits: COMPARTMENTS | More Info
Parameter | Value |
---|---|
Gene | DDX19A |
Protein Name | DD19A_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | ATP-dependent RNA helicase DDX19A (EC 3.6.4.13) (DDX19-like protein) (DEAD box protein 19A) |
Protein Family | DEAD box helicase family |
NCBI Gene ID | 55308 |
UniProt ID | Q9NUU7 |
Enzyme Class | 3.6.4.13 |
Molecular Weight | 53975 |
Protein Length | 478 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | ATP + H(2)O = ADP + phosphate. |
Localization | Cytoplasm Note=Nuclear pore complex cytoplasmic fibrils. |
Function (UniProt annotation) | ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19 functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins (By similarity). |
Gene Ontology | GO:0003723; GO:0004386; GO:0005524; GO:0005643; GO:0005737; GO:0015031; GO:0016020; GO:0031965; GO:0051028 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
CHEK1 (O14757) | Homo sapiens | S92 | SPLYSVKSFEELRLK | 0.446 | 0.4186 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found