CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	ADD3
Protein Name	ADDG_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Gamma-adducin (Adducin-like protein 70)
Protein Family	Aldolase class II family
NCBI Gene ID	120
UniProt ID	Q9UEY8
Enzyme Class	-
Molecular Weight	79155
Protein Length	706
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein; Cytoplasmic side.
Function (UniProt annotation)	Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Plays a role in actin filament capping (PubMed:23836506). Binds to calmodulin.
Gene Ontology	GO:0000794; GO:0005198; GO:0005200; GO:0005516; GO:0005654; GO:0005829; GO:0005856; GO:0005886; GO:0005903; GO:0005911; GO:0005938; GO:0014069; GO:0016020; GO:0030507; GO:0044853; GO:0051015; GO:0051016; GO:0051017; GO:0055085

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CHEK1 (O14757)	Homo sapiens	S693	KKKFRTPSFLKKNKK	0.971	0.5707	-	-	-	-	-	-	in-vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found