| Gene |
EVL
|
| Protein Name |
EVL_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Ena/VASP-like protein (Ena/vasodilator-stimulated phosphoprotein-like) |
| Protein Family |
Ena/VASP family |
| NCBI Gene ID |
51466
|
| UniProt ID |
Q9UI08
|
| Enzyme Class |
- |
| Molecular Weight |
44620 |
| Protein Length |
416 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm, cytoskeleton |
| Function (UniProt annotation) |
Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. |
| Gene Ontology |
GO:0003779; GO:0005522; GO:0005737; GO:0005829; GO:0005856; GO:0005925; GO:0007015; GO:0007166; GO:0007399; GO:0007411; GO:0008154; GO:0009887; GO:0010633; GO:0016020; GO:0017124; GO:0030027; GO:0045010; GO:0045335; GO:0051289; GO:0051496; GO:0071346; GO:1900028 |
