| Gene |
DDX19B
|
| Protein Name |
DD19B_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
ATP-dependent RNA helicase DDX19B (EC 3.6.4.13) (DEAD box RNA helicase DEAD5) (DEAD box protein 19B) |
| Protein Family |
DEAD box helicase family |
| NCBI Gene ID |
11269
|
| UniProt ID |
Q9UMR2
|
| Enzyme Class |
3.6.4.13 |
| Molecular Weight |
53927 |
| Protein Length |
479 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
ATP + H(2)O = ADP + phosphate. |
| Localization |
Cytoplasm. Nucleus, nuclear pore complex. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Note=Nuclear pore complex cytoplasmic fibrils. |
| Function (UniProt annotation) |
ATP-dependent RNA helicase involved in mRNA export from the nucleus. Rather than unwinding RNA duplexes, DDX19B functions as a remodeler of ribonucleoprotein particles, whereby proteins bound to nuclear mRNA are dissociated and replaced by cytoplasmic mRNA binding proteins. |
| Gene Ontology |
GO:0003723; GO:0004386; GO:0005524; GO:0005635; GO:0005643; GO:0005737; GO:0006406; GO:0016020; GO:0031965; GO:0070062 |
