CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	SRRM2
Protein Name	SRRM2_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)
Protein Family	CWC21 family
NCBI Gene ID	23524
UniProt ID	Q9UQ35
Enzyme Class	-
Molecular Weight	299615
Protein Length	2752
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Nucleus speckle.
Function (UniProt annotation)	Involved in pre-mRNA splicing. May function at or prior to the first catalytic step of splicing at the catalytic center of the spliceosome. May do so by stabilizing the catalytic center or the position of the RNA substrate (By similarity). Binds to RNA.
Gene Ontology	GO:0000398; GO:0003723; GO:0005634; GO:0005654; GO:0015030; GO:0016607; GO:0047485; GO:0070742; GO:0071007; GO:0071013

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CHEK1 (O14757)	Homo sapiens	S2280	PRTAVAPSAVNLADP	0.734	0.6531	-	-	-	-	-	-	in-vitro
CHEK1 (O14757)	Homo sapiens	S1499	TPRPRSRSPSSPELN	0.587	0.9381	-	-	-	-	-	-	in-vitro
CHEK1 (O14757)	Homo sapiens	S2388	TSPRVPLSAYERVSG	0.345	0.6906	-	-	-	-	-	-	in-vitro
CHEK1 (O14757)	Homo sapiens	S1497	PQTPRPRSRSPSSPE	0.366	0.9677	-	-	-	-	-	-	in-vitro
CHEK1 (O14757)	Homo sapiens	T2252	ARTPAIPTAVNLADS	0.049	0.6375	-	-	-	-	-	-	in-vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found