| Gene |
YBX2
|
| Protein Name |
YBOX2_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Y-box-binding protein 2 (Contrin) (DNA-binding protein C) (Dbpc) (Germ cell-specific Y-box-binding protein) (MSY2 homolog) |
| Protein Family |
N/A |
| NCBI Gene ID |
51087
|
| UniProt ID |
Q9Y2T7
|
| Enzyme Class |
- |
| Molecular Weight |
38518 |
| Protein Length |
364 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm |
| Function (UniProt annotation) |
Major constituent of messenger ribonucleoprotein particles (mRNPs). Involved in the regulation of the stability and/or translation of germ cell mRNAs. Binds to Y-box consensus promoter element. Binds to full-length mRNA with high affinity in a sequence-independent manner. Binds to short RNA sequences containing the consensus site 5'-UCCAUCA-3' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. May mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay (By similarity). |
| Gene Ontology |
GO:0000981; GO:0001650; GO:0003677; GO:0003723; GO:0005634; GO:0005737; GO:0006366; GO:0007283; GO:0009386; GO:0048599; GO:0120162 |
