CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	PTRH2
Protein Name	PTH2_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Peptidyl-tRNA hydrolase 2, mitochondrial (PTH 2) (EC 3.1.1.29) (Bcl-2 inhibitor of transcription 1)
Protein Family	PTH2 family
NCBI Gene ID	51651
UniProt ID	Q9Y3E5
Enzyme Class	3.1.1.29
Molecular Weight	19194
Protein Length	179
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	N-substituted aminoacyl-tRNA + H(2)O = N-substituted amino acid + tRNA.
Localization	Mitochondrion.
Function (UniProt annotation)	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.
Gene Ontology	GO:0004045; GO:0005739; GO:0005829; GO:0006915; GO:0010629; GO:0016020; GO:2000210; GO:2000811

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
PRKD1 (Q15139)	Homo sapiens	S5	___MPSKSLVMEYLA	0.304	0.2715	-	-	-	-	-	-	In vivo
PRKD1 (Q15139)	Homo sapiens	S87	GKVAAQCSHAAVSAY	0.357	0.1759	-	-	-	-	-	-	In vitro and in vivo

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found