| Gene |
KIF3A
|
| Protein Name |
KIF3A_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Kinesin-like protein KIF3A (Microtubule plus end-directed kinesin motor 3A) |
| Protein Family |
TRAFAC class myosin-kinesin ATPase superfamily |
| NCBI Gene ID |
11127
|
| UniProt ID |
Q9Y496
|
| Enzyme Class |
- |
| Molecular Weight |
80041 |
| Protein Length |
699 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Cytoplasm, cytoskeleton |
| Function (UniProt annotation) |
Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitement of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole. |
| Gene Ontology |
GO:0003777; GO:0005524; GO:0005813; GO:0005814; GO:0005829; GO:0005871; GO:0005874; GO:0005929; GO:0006890; GO:0006996; GO:0007018; GO:0007411; GO:0008017; GO:0008089; GO:0008574; GO:0010457; GO:0015031; GO:0015630; GO:0016887; GO:0016939; GO:0017137; GO:0019886; GO:0019903; GO:0030507; GO:0034454; GO:0035735; GO:0060271; GO:0070062; GO:0072383; GO:0097542; GO:1902414; GO:1904115 |
