CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	PEA15
Protein Name	PEA15_CRIGR
Organism	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Alternative name(s)	Astrocytic phosphoprotein PEA-15 (15 kDa phosphoprotein enriched in astrocytes)
Protein Family	N/A
NCBI Gene ID	100736554
UniProt ID	Q9Z297
Enzyme Class	-
Molecular Weight	15040
Protein Length	130
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	Cytoplasm. Note=Associated with microtubules.
Function (UniProt annotation)	Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface (By similarity). Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm.
Gene Ontology	GO:0000077; GO:0005634; GO:0005829; GO:0006915; GO:0008643; GO:0046325; GO:1902042; GO:1902043

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CAMK2A (Q9UQM7)	Homo sapiens	S116	KDIIRQPSEEEIIKL	N/A	0.4087	-	-	-	-	-	-	In vitro

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

No KEGG pathways found

No NCI Nature pathways found